Monday, January 16, 2012

American Diabetes Association - 2012 Recommendations

In the Diabetes Care, January supplement, ADA has published 2012 recommendations.  The following posts are some of highlights of the recommendations and comparison against the CDA 2008 recommendations:

Criteria for testing diabetes in asymptomatic adult individuals (ADA recommendations)
1.       Testing should be considered in all adults who are overweight (BMI ≥ 25kg/m2) and who have one or more additional risk factors:
·         Physical inactivity
·         First-degree relative with diabetes
·         High-risk race/ethnicity (e.g., African American, Latino, Native American, Asian American, Pacific Islander)
·         Women who delivered a baby weighing > 9 lb or who were diagnosed with GDM
·         Hypertension (BP≥140/90 mmHg or on therapy for hypertension
·         HDL < 0.90 mmol/L and/or TG > 2.82 mmol/L
·         Women with PCOS
·         A1C ≥ 7.5%, IGT, or IFG on previous testing
·         Other clinical conditions associated with insulin resistance (e.g., severe obesity, acanthosis nigricans)
·         History of CVD
2.       In the absence of the above criteria, testing for diabetes should begin at age 45 years
3.     If results are normal, testing should be repeated at least at 3-year intervals, with consideration of more frequent testing depending on initial results (e.g., those with prediabetes should be tested yearly) and risk status.

NOTE: CDA guidelines recommend screening for diabetes every 3 years in individuals ≥ 40 years of age.  More frequent and/or earlier testing should be considered in people with additional risk factors for diabetes (same risk factors as ADA, but also includes schizophrenia and other risk factors in appendix 1, S194 of 2008 recommendations.)

Bottomline:  ADA recommendations are more strict with screening for diabetes

Friday, January 13, 2012

Diagnosis of Diabetes

Did you know that A1C > or = 6.5% using a standardized, validated assay, in the absence of conditions that affect the accuracy of the A1C can be used to diagnose diabetes?

There is a position states by the Canadian Diabetes Association that was posted in July 2011 - http://www.diabetes.ca/documents/for-professionals/CJD--July_2011--Position_Statement.pdf

For factors that can affect A1C include erythropoiesis, altered hemoglobin, alcoholism, chronic renal failure, erythrocyte destruction, assays, etc.  See website above for more detailed information.