Folic acid 5mg & obesity (BMI>30kg/m2)

At the CDA 2011 conference, folic acid 5mg/d is recommended for patients with Type 2 DM and obesity > 30kg/m2.  This is based on a theoretical "evidence" - where a larger volume of distribution requires a larger dose of folic acid.  Why 5mg?  Because it comes in a 5mg tablet (prescription only).  No direct evidence to support or refute this recommendation.